Base Model and Enclosure configuration 532 nm: 100-4350* cm-1 785 nm: 100-3425* cm-1 1000 nm: 200-2400 cm-1 Hybrid 785 nm: 150-1890** cm-1 *Low signal-to-noise ratio at <150 cm-1 **Low signal-to-noise ratio at <175 cm-1
The Raman Rxn4 analyzer powered by Kaiser Raman technology is the optimal choice for manufacturing or process environments. Raman Rxn4 provides high-resolution performance for in situ, real-time measurement and control. It features unique self-monitoring, diagnostics, and self-calibration to ensure the validity of each measurement. Stackable in a standard 19" rack, the Raman Rxn4 saves valuable space on the production floor. It is also offered with an optional stainless steel NEMA 4X enclosure.
KBI Biopharma is monitoring a diverse array of cell lines and cell concentrations in minimal volume for automated cell cultivation in the Life Sciences industry.
Raman downstream process measurement of biosimilars - Alvotech’s testing of the protein purification process during ultrafiltration/diafiltration (UF/DF)
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
Base Model and Enclosure configuration 532 nm: 100-4350* cm-1 785 nm: 100-3425* cm-1 1000 nm: 200-2400 cm-1 Hybrid 785 nm: 150-1890** cm-1 *Low signal-to-noise ratio at <150 cm-1 **Low signal-to-noise ratio at <175 cm-1
Spectral resolution
Base model and Enclosure configuration (average): 5 cm-1 (532 nm) 4 cm-1 (785 nm) 6 cm-1 (1000 nm) Hybrid: 4 cm-1 (785 nm) average
Channels
Base model and Enclosure configuration: Up to four channels Hybrid: Up to two channels
Ambient temperature
Base model: Operating: 5 to 35 °C / 41 to 95 °F (532 nm, 785 nm) 5 to 30 °C / 41 to 86 °F (1000 nm) Storage: -15 to 50 °C / 5 to 122 °F Hybrid: Operating: 5 to 35 °C / 41 to 95 °F Storage: -15 to 50 °C / 5 to 122 °F Enclosure configuration: Operating: (all wavelengths) 5 to 50 °C / 41 to 122 °F Storage: -15 to 50 °C / 5 to 122 °F
Relative humidity
Base model and hybrid: 20 to 80 %, non-condensing Enclosure configuration: Up to 80 % for temperature range 5 to 31 °C (41 to 87.8 °F), decreasing linearly to 20 % at 50 °C (122 °F)
Input voltage
Base model and Hybrid: 100-240 V, 50-60 Hz, ±10% Enclosure configuration: 120 V ±10%, 60 Hz -OR- 230 V ±10%, 50/60 Hz
Power consumption (W)
Base model and Hybrid: 400 (max) 250 (typical start-up) 120 (typical running) Enclosure configuration: 1560 (max) 1560 (typical start-up) 750 (typical running)
Warm up time (minutes)
Base model and Hybrid: 120 Enclosure configuration: 240
Unit dimensions (width x height x depth)
Base model and Hybrid: 483 x 267 x 556 mm 19.02 x 10.52 x 21.89 inch Enclosure configuration: (with optional trolley) 1175 x 1480 x 826 mm 46.26 x 58.27 x 32.52 inch
Weight
Base model: 28.5 kg / 63 lb Enclosure configuration: 185.5 kg / 409 lb (with optional trolley)
Base Model and Enclosure configuration 532 nm: 100-4350* cm-1 785 nm: 100-3425* cm-1 1000 nm: 200-2400 cm-1 Hybrid 785 nm: 150-1890** cm-1 *Low signal-to-noise ratio at <150 cm-1 **Low signal-to-noise ratio at <175 cm-1
Spectral resolution
Base model and Enclosure configuration (average): 5 cm-1 (532 nm) 4 cm-1 (785 nm) 6 cm-1 (1000 nm) Hybrid: 4 cm-1 (785 nm) average
Channels
Base model and Enclosure configuration: Up to four channels Hybrid: Up to two channels
Ambient temperature
Base model: Operating: 5 to 35 °C / 41 to 95 °F (532 nm, 785 nm) 5 to 30 °C / 41 to 86 °F (1000 nm) Storage: -15 to 50 °C / 5 to 122 °F Hybrid: Operating: 5 to 35 °C / 41 to 95 °F Storage: -15 to 50 °C / 5 to 122 °F Enclosure configuration: Operating: (all wavelengths) 5 to 50 °C / 41 to 122 °F Storage: -15 to 50 °C / 5 to 122 °F
Relative humidity
Base model and hybrid: 20 to 80 %, non-condensing Enclosure configuration: Up to 80 % for temperature range 5 to 31 °C (41 to 87.8 °F), decreasing linearly to 20 % at 50 °C (122 °F)
Input voltage
Base model and Hybrid: 100-240 V, 50-60 Hz, ±10% Enclosure configuration: 120 V ±10%, 60 Hz -OR- 230 V ±10%, 50/60 Hz
Power consumption (W)
Base model and Hybrid: 400 (max) 250 (typical start-up) 120 (typical running) Enclosure configuration: 1560 (max) 1560 (typical start-up) 750 (typical running)
Warm up time (minutes)
Base model and Hybrid: 120 Enclosure configuration: 240
Unit dimensions (width x height x depth)
Base model and Hybrid: 483 x 267 x 556 mm 19.02 x 10.52 x 21.89 inch Enclosure configuration: (with optional trolley) 1175 x 1480 x 826 mm 46.26 x 58.27 x 32.52 inch
Weight
Base model: 28.5 kg / 63 lb Enclosure configuration: 185.5 kg / 409 lb (with optional trolley)
Sampling probe compatibility
Base model and enclosure configuration: Raman Rxn-10 (with accessory optics) Hybrid: Channel 1 - Raman Rxn-20 (with accessory optics) Channel 2 - Raman Rxn-10 (with accessory optics)
Automation interface
OPC Modbus HTTPS (contact us for other options)
Installation options
Base model and Hybrid: 19-inch rack package Enclosure configuration: NEMA 4X enclosure; wall-mountable, moblile trolley, or fixed stand
Hazardous area certifications
Base model and Hybrid: ATEX, CSA, IECEx, UKCA, JPEx Enclosure configuration: Call support for options
Measuring principle
Raman spectroscopy
Laser wavelength
Base model: 532 nm Enclosure configuration: 532 nm
Spectral coverage
Base Model and Enclosure configuration 532 nm: 100-4350* cm-1 *Low signal-to-noise ratio at <150 cm-1
Spectral resolution
Base model and Enclosure configuration (average): 5 cm-1 (532 nm)
Channels
Base model and Enclosure configuration: Up to four channels
Ambient temperature
Base model: Operating: 5 to 35 °C / 41 to 95 °F Storage: -15 to 50 °C / 5 to 122 °F Enclosure configuration: Operating: 5 to 50 °C / 41 to 122 °F Storage: -15 to 50 °C / 5 to 122 °F
Relative humidity
Base model and hybrid: 20 to 80 %, non-condensing Enclosure configuration: Up to 80 % for temperature range 5 to 31 °C (41 to 87.8 °F), decreasing linearly to 20 % at 50 °C (122 °F)
Input voltage
Base model: 100-240 V, 50-60 Hz, ±10% Enclosure configuration: 120 V ±10%, 60 Hz -OR- 230 V ±10%, 50/60 Hz
Base model and Hybrid: 483 x 267 x 556 mm 19.02 x 10.52 x 21.89 inch Enclosure configuration: (with optional trolley) 1175 x 1480 x 826 mm 46.26 x 58.27 x 32.52 inch
Weight
Base model: 28.5 kg / 63 lb Enclosure configuration: 185.5 kg / 409 lb (with optional trolley)
Sampling probe compatibility
Raman Rxn-10 with accessory optics Raman Rxn-40 Raman Rxn-41
Automation interface
OPC Modbus HTTPS (contact us for other options)
Installation options
Base model and Hybrid: 19-inch rack package Enclosure configuration: NEMA 4X enclosure; wall-mountable, moblile trolley, or fixed stand
Hazardous area certifications
Base model and Hybrid: ATEX, CSA, IECEx, UKCA, JPEx Enclosure configuration: Call support for options
Advanced process and product control in fermentations -
Raman spectroscopy for composition analysis in a lab
or process
PU (Publication)
English version - 03/2022
New version available in English
An overview of Raman spectroscopy analyzer systems (including the Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, and Rxn-45 probe), powered by Kaiser Raman technology, for fermentation compositional analysis in a lab or process applicable to biotechnology in the food & beverage industry.
Kaiser Raman technology and Sartorius BioPAT Spectro® collaboration
Q&A - Scalable, real-time bioprocess monitoring solutions
PU (Publication)
English version - 12/2021
New version available in English
A Q&A about how our Raman spectroscopy analyzer systems (including the Raman Rxn2 analyzer, Raman Rxn4 analyzer, and Rxn-46 probe), powered by Kaiser Raman technology, integrates with the Sartorius BioPAT Spectro platform (Ambr and biostat STR) for high throughput and single use (SUB) bioprocessingin the biopharmaceutical life science industry.
Raman application guide for the life science industry -
Trusted composition analysis for the life sciences
PU (Publication)
English version - 04/2022
New version available in English
A guide to our Raman spectroscopy application notes for the Life Science industry (featuring the Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, Rxn-20 probe, Rxn-45 probe, Rxn-46 probe, and probe accessory optics (bIO-Optic, Raman single use optic system / SUB, immersion optic, non-contact optic).
Endress+Hauser - your one-source Life Sciences technology partner
PU (Publication)
English version - 06/2024
New version available in English
Graphic highlighting why Endress+Hauser is trusted by the world's top biopharmaceutical manufacturers for its Life Sciences expertise and reliable inline, real-time measurement technologies like Raman spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Prioritize scalability for an efficient biopharmaceutical
product development lifecycle
PU (Publication)
Czech version - 09/2024
New version available in English
This technical paper studies the importance of scalability as a competitive advantage in bioprocessing in the Life Science industry, and Endress+Hauser's scalable Raman systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology and Liquid Analysis portfolio (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Raman data library -- Faster time to market with
increased insight, productivity, and data integrity
PU (Publication)
English version - 06/2024
New version available in English
This document provides insight into the core and cGxP features of Raman data library (data organization, visualization, user management, and univariate analysis for Raman Rxn2 and Raman Rxn4 analyzers), while also addressing common questions regarding the software's functionalities.
